Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

por Yelick, Julia, Men, Yuqin, Jin, Shijie, Seo, Sabrina, Espejo-Porras, Francisco, Yang, Yongjie
Publicado en Exp Neurol (2020)

A Versatile Chemo-Enzymatic Conjugation Approach Yields Homogeneous and Highly Potent Antibody-Drug Conjugates

por Xu, Ying, Jin, Shijie, Zhao, Wenbin, Liu, Wenhui, Ding, Ding, Zhou, Jie, Chen, Shuqing
Publicado en Int J Mol Sci (2017)

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

por Mizuno, Tetsuya, Doi, Yukiko, Mizoguchi, Hiroyuki, Jin, Shijie, Noda, Mariko, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Suzumura, Akio
Publicado 2011

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

por Jin, Shijie, Sonobe, Yoshifumi, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Publicado en PLoS One (2014)

TCR-mimic antibody-drug conjugates targeting intracellular tumor-specific mutant antigen KRAS G12V mutation

por Shen, Ying, Wei, Xiaoyue, Jin, Shijie, Wu, Yue, Zhao, Wenbin, Xu, Yingchun, Pan, Liqiang, Zhou, Zhan, Chen, Shuqing
Publicado en Asian J Pharm Sci (2020)

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

por Doi, Yukiko, Mizuno, Tetsuya, Maki, Yuki, Jin, Shijie, Mizoguchi, Hiroyuki, Ikeyama, Masayoshi, Doi, Minoru, Michikawa, Makoto, Takeuchi, Hideyuki, Suzumura, Akio
Publicado 2009

Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons

por Doi, Yukiko, Takeuchi, Hideyuki, Horiuchi, Hiroshi, Hanyu, Taketo, Kawanokuchi, Jun, Jin, Shijie, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Publicado 2013

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

por Wang, Yue, Jin, Shijie, Sonobe, Yoshifumi, Cheng, Yi, Horiuchi, Hiroshi, Parajuli, Bijay, Kawanokuchi, Jun, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Publicado 2014

Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

por Watanabe, Seiji, Ilieva, Hristelina, Tamada, Hiromi, Nomura, Hanae, Komine, Okiru, Endo, Fumito, Jin, Shijie, Mancias, Pedro, Kiyama, Hiroshi, Yamanaka, Koji
Publicado en EMBO Mol Med (2016)

Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS

por Men, Yuqin, Yelick, Julia, Jin, Shijie, Tian, Yang, Chiang, Ming Sum R., Higashimori, Haruki, Brown, Eoin, Jarvis, Rachel, Yang, Yongjie
Publicado en Nat Commun (2019)

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation

por Horiuchi, Hiroshi, Parajuli, Bijay, Komiya, Hiroyasu, Ogawa, Yuki, Jin, Shijie, Takahashi, Keita, Azuma, Yasu-Taka, Tanaka, Fumiaki, Suzumura, Akio, Takeuchi, Hideyuki
Publicado en Front Immunol (2021)

Interleukin-25 Expressed by Brain Capillary Endothelial Cells Maintains Blood-Brain Barrier Function in a Protein Kinase Cϵ-dependent Manner

por Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Publicado 2009

Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin

por Doi, Yukiko, Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Fukumoto, Kazuya, Horiuchi, Hiroshi, Jin, Shijie, Kawanokuchi, Jun, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Publicado 2014

Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cϵ-dependent manner.

por Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Publicado en J Biol Chem (2016)

Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway

por Kohei Nishino, Seiji Watanabe, Jin Shijie, Yuri Murata, Kotaro Oiwa, Okiru Komine, Fumito Endo, Hitomi Tsuiji, Manabu Abe, Kenji Sakimura, Amit Mishra, Koji Yamanaka
Publicado 2019-07-01

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

por Wang, Jinyan, Takeuchi, Hideyuki, Sonobe, Yoshifumi, Jin, Shijie, Mizuno, Tetsuya, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu, Kato, Takuma, Muramatsu, Hisako, Muramatsu, Takashi, Suzumura, Akio
Publicado 2008

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

por Komine, Okiru, Yamashita, Hirofumi, Fujimori-Tonou, Noriko, Koike, Masato, Jin, Shijie, Moriwaki, Yasuhiro, Endo, Fumito, Watanabe, Seiji, Uematsu, Satoshi, Akira, Shizuo, Uchiyama, Yasuo, Takahashi, Ryosuke, Misawa, Hidemi, Yamanaka, Koji
Publicado en Cell Death Differ (2018)

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

por Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Doi, Yukiko, Jin, Shijie, Noda, Mariko, Liang, Jianfeng, Li, Hua, Zhou, Yan, Mori, Rarami, Yasuoka, Satoko, Li, Endong, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Sato, Jun, Yamanaka, Koji, Sobue, Gen, Mizuno, Tetsuya, Suzumura, Akio
Publicado 2011