Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

von Yelick, Julia, Men, Yuqin, Jin, Shijie, Seo, Sabrina, Espejo-Porras, Francisco, Yang, Yongjie
Veröffentlicht in Exp Neurol (2020)

A Versatile Chemo-Enzymatic Conjugation Approach Yields Homogeneous and Highly Potent Antibody-Drug Conjugates

von Xu, Ying, Jin, Shijie, Zhao, Wenbin, Liu, Wenhui, Ding, Ding, Zhou, Jie, Chen, Shuqing
Veröffentlicht in Int J Mol Sci (2017)

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

von Mizuno, Tetsuya, Doi, Yukiko, Mizoguchi, Hiroyuki, Jin, Shijie, Noda, Mariko, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Suzumura, Akio
Veröffentlicht 2011

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

von Jin, Shijie, Sonobe, Yoshifumi, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Veröffentlicht in PLoS One (2014)

TCR-mimic antibody-drug conjugates targeting intracellular tumor-specific mutant antigen KRAS G12V mutation

von Shen, Ying, Wei, Xiaoyue, Jin, Shijie, Wu, Yue, Zhao, Wenbin, Xu, Yingchun, Pan, Liqiang, Zhou, Zhan, Chen, Shuqing
Veröffentlicht in Asian J Pharm Sci (2020)

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

von Doi, Yukiko, Mizuno, Tetsuya, Maki, Yuki, Jin, Shijie, Mizoguchi, Hiroyuki, Ikeyama, Masayoshi, Doi, Minoru, Michikawa, Makoto, Takeuchi, Hideyuki, Suzumura, Akio
Veröffentlicht 2009

Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons

von Doi, Yukiko, Takeuchi, Hideyuki, Horiuchi, Hiroshi, Hanyu, Taketo, Kawanokuchi, Jun, Jin, Shijie, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Veröffentlicht 2013

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

von Wang, Yue, Jin, Shijie, Sonobe, Yoshifumi, Cheng, Yi, Horiuchi, Hiroshi, Parajuli, Bijay, Kawanokuchi, Jun, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Veröffentlicht 2014

Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

von Watanabe, Seiji, Ilieva, Hristelina, Tamada, Hiromi, Nomura, Hanae, Komine, Okiru, Endo, Fumito, Jin, Shijie, Mancias, Pedro, Kiyama, Hiroshi, Yamanaka, Koji
Veröffentlicht in EMBO Mol Med (2016)

Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS

von Men, Yuqin, Yelick, Julia, Jin, Shijie, Tian, Yang, Chiang, Ming Sum R., Higashimori, Haruki, Brown, Eoin, Jarvis, Rachel, Yang, Yongjie
Veröffentlicht in Nat Commun (2019)

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation

von Horiuchi, Hiroshi, Parajuli, Bijay, Komiya, Hiroyasu, Ogawa, Yuki, Jin, Shijie, Takahashi, Keita, Azuma, Yasu-Taka, Tanaka, Fumiaki, Suzumura, Akio, Takeuchi, Hideyuki
Veröffentlicht in Front Immunol (2021)

Interleukin-25 Expressed by Brain Capillary Endothelial Cells Maintains Blood-Brain Barrier Function in a Protein Kinase Cϵ-dependent Manner

von Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Veröffentlicht 2009

Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin

von Doi, Yukiko, Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Fukumoto, Kazuya, Horiuchi, Hiroshi, Jin, Shijie, Kawanokuchi, Jun, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Veröffentlicht 2014

Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cϵ-dependent manner.

von Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Veröffentlicht in J Biol Chem (2016)

Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway

von Kohei Nishino, Seiji Watanabe, Jin Shijie, Yuri Murata, Kotaro Oiwa, Okiru Komine, Fumito Endo, Hitomi Tsuiji, Manabu Abe, Kenji Sakimura, Amit Mishra, Koji Yamanaka
Veröffentlicht 2019-07-01

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

von Wang, Jinyan, Takeuchi, Hideyuki, Sonobe, Yoshifumi, Jin, Shijie, Mizuno, Tetsuya, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu, Kato, Takuma, Muramatsu, Hisako, Muramatsu, Takashi, Suzumura, Akio
Veröffentlicht 2008

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

von Komine, Okiru, Yamashita, Hirofumi, Fujimori-Tonou, Noriko, Koike, Masato, Jin, Shijie, Moriwaki, Yasuhiro, Endo, Fumito, Watanabe, Seiji, Uematsu, Satoshi, Akira, Shizuo, Uchiyama, Yasuo, Takahashi, Ryosuke, Misawa, Hidemi, Yamanaka, Koji
Veröffentlicht in Cell Death Differ (2018)

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

von Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Doi, Yukiko, Jin, Shijie, Noda, Mariko, Liang, Jianfeng, Li, Hua, Zhou, Yan, Mori, Rarami, Yasuoka, Satoko, Li, Endong, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Sato, Jun, Yamanaka, Koji, Sobue, Gen, Mizuno, Tetsuya, Suzumura, Akio
Veröffentlicht 2011