Current Concepts in Therapeutic Strategies Targeting Cognitive Decline and Disease Modification in Alzheimer’s Disease

par Jacobsen, J. Steven, Reinhart, Peter, Pangalos, Menelas N.
Publié 2005

Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate

par Hook, Gregory, Jacobsen, J. Steven, Grabstein, Kenneth, Kindy, Mark, Hook, Vivian
Publié dans Front Neurol (2015)

Characterization of endogenous APP processing in a cell-free system

par Brown, Abraham M., Potempska, Anna, Tummolo, Donna, Spruyt, Michael A., Jacobsen, J. Steven, Sonnenberg-Reines, June
Publié 1998

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

par Jacobsen, J. Steven, Wu, Chi-Cheng, Redwine, Jeffrey M., Comery, Thomas A., Arias, Robert, Bowlby, Mark, Martone, Robert, Morrison, John H., Pangalos, Menelas N., Reinhart, Peter H., Bloom, Floyd E.
Publié 2006

Penetrating Traumatic Brain Injury Triggers Dysregulation of Cathepsin B Protein Levels Independent of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid

par Boutté, Angela M., Hook, Vivian, Thangavelu, Bharani, Sarkis, George Anis, Abbatiello, Brittany N., Hook, Gregory, Jacobsen, J. Steven, Robertson, Claudia S., Gilsdorf, Janice, Yang, Zhihui, Wang, Kevin K.W., Shear, Deborah A.
Publié dans J Neurotrauma (2020)

Acute γ-Secretase Inhibition Improves Contextual Fear Conditioning in the Tg2576 Mouse Model of Alzheimer's Disease

par Comery, Thomas A., Martone, Robert L., Aschmies, Suzan, Atchison, Kevin P., Diamantidis, George, Gong, Xiaohai, Zhou, Hua, Kreft, Anthony F., Pangalos, Menelas N., Sonnenberg-Reines, June, Jacobsen, J. Steven, Marquis, Karen L.
Publié dans J Neurosci (2005)

Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer Disease

par Basi, Guriqbal S., Feinberg, Hadar, Oshidari, Farshid, Anderson, John, Barbour, Robin, Baker, Jeanne, Comery, Thomas A., Diep, Linnea, Gill, Davinder, Johnson-Wood, Kelly, Goel, Amita, Grantcharova, Katerina, Lee, Mike, Li, Jingzhi, Partridge, Anthony, Griswold-Prenner, Irene, Piot, Nicolas, Walker, Don, Widom, Angela, Pangalos, Menelas N., Seubert, Peter, Jacobsen, J. Steven, Schenk, Dale, Weis, William I.
Publié 2010

Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade

par Jacobsen, J. Steven, Comery, Thomas A., Martone, Robert L., Elokdah, Hassan, Crandall, David L., Oganesian, Aram, Aschmies, Suzan, Kirksey, Yolanda, Gonzales, Cathleen, Xu, Jane, Zhou, Hua, Atchison, Kevin, Wagner, Erik, Zaleska, Margaret M., Das, Indranil, Arias, Robert L., Bard, Jonathan, Riddell, David, Gardell, Stephen J., Abou-Gharbia, Magid, Robichaud, Albert, Magolda, Ronald, Vlasuk, George P., Bjornsson, Thorir, Reinhart, Peter H., Pangalos, Menelas N.
Publié 2008