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Characterization of endogenous APP processing in a cell-free system

We have developed a simple in vitro assay using tissue homogenates that allows detection and characterization of several endogenous proteolytic activities which convert Alzheimer’s amyloid precursor protein (APP) to the smaller, carboxy-terminal fragments, postulated to be intermediates in the forma...

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Podrobná bibliografie
Hlavní autoři: Brown, Abraham M., Potempska, Anna, Tummolo, Donna, Spruyt, Michael A., Jacobsen, J. Steven, Sonnenberg-Reines, June
Médium: Artigo
Jazyk:Inglês
Vydáno: Kluwer Academic Publishers 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455769/
https://ncbi.nlm.nih.gov/pubmed/23604330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-998-0003-y
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