Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate

समान संसाधन

• The Cysteine Protease Cathepsin B Is a Key Drug Target and Cysteine Protease Inhibitors Are Potential Therapeutics for Traumatic Brain Injury
  द्वारा: Hook, Gregory R., और अन्य
  प्रकाशित: (2014)
• Brain Pyroglutamate Amyloid-Beta is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer’s Disease Therapeutic
  द्वारा: Hook, Gregory, और अन्य
  प्रकाशित: (2014)
• The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer’s disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity
  द्वारा: Hook, Gregory, और अन्य
  प्रकाशित: (2011)
• Cysteine Cathepsins in the Secretory Vesicle Produce Active Peptides: Cathepsin L Generates Peptide Neurotransmitters and Cathepsin B Produces Beta-Amyloid of Alzheimer’s Disease
  द्वारा: Hook, Vivian, और अन्य
  प्रकाशित: (2011)
• Pharmacogenetic Features of Inhibitors to Cathepsin B that Improve Memory Deficit and Reduce Beta-Amyloid Related to Alzheimer’s Disease
  द्वारा: Hook, Vivian, और अन्य
  प्रकाशित: (2010)