Randomized Phase II Designs

Por Rubinstein, Larry, Crowley, John, Ivy, Percy, LeBlanc, Michael, Sargent, Dan
Publicado em 2009

Rapid Development of Hypertension and Proteinuria with Cediranib, an Oral Vascular Endothelial Growth Factor Receptor Inhibitor

Por Robinson, Emily S., Matulonis, Ursula A., Ivy, Percy, Berlin, Suzanne T., Tyburski, Karin, Penson, Richard T., Humphreys, Benjamin D.
Publicado em 2010

Population Pharmacokinetics of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone (Triapine®) in Cancer Patients

Por Kolesar, Jill, Brundage, Richard C., Pomplun, Marcia, Alberti, Dona, Holen, Kyle, Traynor, Anne, Ivy, Percy, Wilding, George
Publicado em 2010

A phase II study of 17-allylamino-17-demethoxygeldanamycin in metastatic or locally advanced, unresectable breast cancer

Por Gartner, Elaina M., Silverman, Paula, Simon, Michael, Flaherty, Lawrence, Abrams, Judith, Ivy, Percy, LoRusso, Patricia M.
Publicado em 2011

Brief Report: Phase II Trial of Rebeccamycin Analogue, a Dual Topoisomerase I and II Inhibitor, in Relapsed “Sensitive” Small Cell Lung Cancer

Por Schwandt, Anita, Mekhail, Tarek, Halmos, Balazs, O'Brien, Timothy, Ma, Patrick C., Fu, Pingfu, Ivy, Percy, Dowlati, Afshin
Publicado em 2012

Tolerance and Activity of Oxaliplatin with Protracted Topotecan Infusion In Patients With Previously Treated Ovarian Cancer. A phase I study

Por Hochster, Howard, Chen, Thomas T., Lu, Janice M., Hills, Day, Sorich, Joan, Escalon, Juliet, Ivy, Percy, Liebes, Leonard, Muggia, Franco
Publicado em 2008

Notch1 phenotype and clinical stage progression in non-small cell lung cancer

Por Nguyen, Dat, Rubinstein, Larry, Takebe, Naoko, Miele, Lucio, Tomaszewski, Joseph E, Ivy, Percy, Doroshow, James H, Yang, Sherry X
Publicado no J Hematol Oncol (2015)

Case Example of Dose Optimization Using Data From Bortezomib Dose-Finding Clinical Trials

Por Lee, Shing M., Backenroth, Daniel, Cheung, Ying Kuen Ken, Hershman, Dawn L., Vulih, Diana, Anderson, Barry, Ivy, Percy, Minasian, Lori
Publicado no J Clin Oncol (2016)

Evaluation of mRNA by Q-RTPCR and Protein Expression by AQUA of the M2 Subunit of Ribonucleotide Reductase (RRM2) in Human Tumors

Por Kolesar, Jill, Huang, Wei, Eickhoff, Jens, Hahn, Kristine, Alberti, Dona, Attia, Steve, Schelman, William, Holen, Kyle, Traynor, Anne, Ivy, Percy, Wilding, George
Publicado em 2008

Phase I Clinical Trial of Ifosfamide, Oxaliplatin and Etoposide (IOE) in Pediatric Patients with Refractory Solid Tumors

Por Lam, Catherine G., Furman, Wayne L., Wang, Chong, Spunt, Sheri L., Wu, Jianrong, Ivy, Percy, Santana, Victor M., McGregor, Lisa M.
Publicado no J Pediatr Hematol Oncol (2015)

Phase 1 Study of XL119, a Rebeccamycin Analog, in Patients With Refractory Hematologic Malignancies

Por Borthakur, Gautam, Alvarado, Yesid, Ravandi-Kashani, Farhad, Cortes, Jorge, Estrov, Zeev, Faderl, Stefan, Ivy, Percy, Bueso-Ramos, Carlos, Bekele, B. Nebiyou, Giles, Francis
Publicado em 2008

Phase I trial of sunitinib and gemcitabine in patients with advanced solid tumors

Por Brell, Joanna M., Krishnamurthi, Smitha S., Rath, Linda, Bokar, Joseph A., Savvides, Panayiotis, Gibbons, Joseph, Cooney, Matthew M., Meropol, Neal J., Ivy, Percy, Dowlati, Afshin
Publicado em 2012

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

Por Gerstner, Elizabeth R., Duda, Dan G., di Tomaso, Emmanuelle, Ryg, Peter A., Loeffler, Jay S., Sorensen, A. Gregory, Ivy, Percy, Jain, Rakesh K., Batchelor, Tracy T.
Publicado no Nat Rev Clin Oncol (2009)

Nomogram to Predict Cycle-One Serious Drug-Related Toxicity in Phase I Oncology Trials

Por Hyman, David M., Eaton, Anne A., Gounder, Mrinal M., Smith, Gary L., Pamer, Erika G., Hensley, Martee L., Spriggs, David R., Ivy, Percy, Iasonos, Alexia
Publicado em 2014

SAFETY, EFFICACY, PHARMACOKINETICS AND PHARMACODYNAMICS OF THE COMBINATION OF SORAFENIB AND TANESPIMYCIN

Por Vaishampayan, Ulka N., Burger, Angelika M., Sausville, Edward A., Heilbrun, Lance K., Li, Jing, Horiba, Naomi, Egorin, Merrill J., Ivy, Percy, Pacey, Simon, Lorusso, Patricia M.
Publicado em 2010

A Phase II Study of Pazopanib in Patients with Recurrent or Metastatic Invasive Breast Carcinoma: A Trial of the Princess Margaret Hospital Phase II Consortium

Por Taylor, Sara K., Chia, Stephen, Dent, Susan, Clemons, Mark, Agulnik, Mark, Grenci, Pamela, Wang, Lisa, Oza, Amit M., Ivy, Percy, Pritchard, Kathleen I., Leighl, Natasha B.
Publicado em 2010

Pharmacodynamic Study Using FLT PET/CT in Patients with Renal Cell Cancer and Other Solid Malignancies Treated with Sunitinib Malate

Por Liu, Glenn, Jeraj, Robert, Vanderhoek, Matt, Perlman, Scott, Kolesar, Jill, Harrison, Michael, Simoncic, Urban, Eickhoff, Jens, Carmichael, Lakeesha, Chao, Bo, Marnocha, Rebecca, Ivy, Percy, Wilding, George
Publicado em 2011

Increased Survival of Glioblastoma Patients who Respond to Anti-angiogenic Therapy with Elevated Blood Perfusion

Por Sorensen, A. Gregory, Emblem, Kyrre E., Polaskova, Pavlina, Jennings, Dominique, Kim, Heisoog, Ancukiewicz, Marek, Wang, Meiyun, Wen, Patrick Y., Ivy, Percy, Batchelor, Tracy T., Jain, Rakesh K.
Publicado em 2011

A Phase II Study of Oxaliplatin Combined with Continuous Infusion Topotecan for Patients with Previously Treated Ovarian Cancer

Por Stein, Stacey M., Tiersten, Amy, Hochster, Howard S., Blank, Stephanie V., Pothuri, Bhavana, Curtin, John, Shapira, Ilan, Levinson, Benjamin, Ivy, Percy, Joseph, Benson, Guddati, Achuta K., Muggia, Franco
Publicado em 2013

Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers

Por Dowlati, Afshin, Posey, James, Ramanathan, Ramesh K., Rath, Linda, Fu, Pingfu, Chak, Amitabh, Krishnamurthi, Smitha, Brell, Joanna, Ingalls, Stephen, Hoppel, Charles L., Ivy, Percy, Remick, Scot C.
Publicado no Cancer Chemother Pharmacol (2009)