Rapid Development of Hypertension and Proteinuria with Cediranib, an Oral Vascular Endothelial Growth Factor Receptor Inhibitor

Background and objectives: Hypertension and proteinuria are common but poorly understood renal toxicities of vascular endothelial growth factor (VEGF) receptor signaling pathway inhibitors. In this phase II study of cediranib (AZD2171) for recurrent epithelial ovarian cancer, the time course and sev...

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Detalhes bibliográficos
Main Authors: Robinson, Emily S., Matulonis, Ursula A., Ivy, Percy, Berlin, Suzanne T., Tyburski, Karin, Penson, Richard T., Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827577/
https://ncbi.nlm.nih.gov/pubmed/20056761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.08111109
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