VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

Most brain tumors oversecrete vascular endothelial growth factor (VEGF), which leads to an abnormally permeable tumor vasculature. This hyperpermeability allows fluid to leak from the intravascular space into the brain parenchyma, which causes vasogenic cerebral edema and increased interstitial flui...

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Foilsithe in:Nat Rev Clin Oncol
Main Authors: Gerstner, Elizabeth R., Duda, Dan G., di Tomaso, Emmanuelle, Ryg, Peter A., Loeffler, Jay S., Sorensen, A. Gregory, Ivy, Percy, Jain, Rakesh K., Batchelor, Tracy T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793889/
https://ncbi.nlm.nih.gov/pubmed/19333229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2009.14
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