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Randomized Phase II Designs

As the use of molecularly targeted agents, which are anticipated to increase overall and progression-free survival (OS and PFS), but not necessarily tumor response, has increased in oncology, there has been a corresponding increase in the recommendation and use of randomized phase II designs. Such d...

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Detalhes bibliográficos
Main Authors: Rubinstein, Larry, Crowley, John, Ivy, Percy, LeBlanc, Michael, Sargent, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774021/
https://ncbi.nlm.nih.gov/pubmed/19276275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2031
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