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Choosing Phase II Endpoints and Designs: Evaluating the possibilities
Selecting the Phase II design and endpoint to achieve the best possible chance of success for a confirmatory Phase III study in a particular disease and treatment setting is challenging but critical. Simulating from existing clinical trial data sets, and mathematical models, can be useful tools for...
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| Publicado en: | Clin Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820349/ https://ncbi.nlm.nih.gov/pubmed/22407830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0454 |
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