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Choosing Phase II Endpoints and Designs: Evaluating the possibilities

Selecting the Phase II design and endpoint to achieve the best possible chance of success for a confirmatory Phase III study in a particular disease and treatment setting is challenging but critical. Simulating from existing clinical trial data sets, and mathematical models, can be useful tools for...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: LeBlanc, Michael, Tangen, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820349/
https://ncbi.nlm.nih.gov/pubmed/22407830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0454
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