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Resampling phase III data to assess phase II trial designs and endpoints

PURPOSE: The best phase II design and endpoint for growth inhibitory agents is controversial. We simulated phase II trials by resampling patients from a positive (sorafenib vs. placebo; TARGET) and a negative (AE941 vs. placebo) phase III trial in metastatic renal cancer to compare the ability of va...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharma, Manish R., Karrison, Theodore G., Jin, Yuyan, Bies, Robert R., Maitland, Michael L., Stadler, Walter M., Ratain, Mark J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328614/
https://ncbi.nlm.nih.gov/pubmed/22287601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1815
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