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Estimation of renal cell carcinoma treatment effects from disease progression modeling

To improve future drug development efficiency in renal cell carcinoma (RCC), a disease progression model was developed with longitudinal tumor size data from a phase III trial of sorafenib in RCC. The best fit model was externally evaluated on 145 placebo-treated patients in a phase III trial of paz...

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Detalhes bibliográficos
Main Authors: Maitland, Michael L., Wu, Kehua, Sharma, Manish R., Jin, Yuyan, Kang, Soonmo Peter, Stadler, Walter M., Karrison, Theodore G., Ratain, Mark J., Bies, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791430/
https://ncbi.nlm.nih.gov/pubmed/23443753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.263
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