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Estimation of renal cell carcinoma treatment effects from disease progression modeling
To improve future drug development efficiency in renal cell carcinoma (RCC), a disease progression model was developed with longitudinal tumor size data from a phase III trial of sorafenib in RCC. The best fit model was externally evaluated on 145 placebo-treated patients in a phase III trial of paz...
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Hauptverfasser: | , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791430/ https://ncbi.nlm.nih.gov/pubmed/23443753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.263 |
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