Molecular basis for primary and secondary tyrosine kinase inhibitor resistance in gastrointestinal stromal tumor

Por Gounder, Mrinal M., Maki, Robert G.
Publicado em 2010

Reply to E. Younger et al

Por Atkinson, Thomas M., Gounder, Mrinal M.
Publicado no J Clin Oncol (2018)

Trametinib in Histiocytic Sarcoma with an Activating MAP2K1 (MEK1) Mutation

Por Gounder, Mrinal M., Solit, David B., Tap, William D.
Publicado no N Engl J Med (2018)

Locally Aggressive Connective Tissue Tumors

Por Gounder, Mrinal M., Thomas, David M., Tap, William D.
Publicado no J Clin Oncol (2018)

Prospective Development of a Patient-Reported Outcomes Instrument for Desmoid Tumors or Aggressive Fibromatosis

Por Gounder, Mrinal M., Maddux, LeAnne, Paty, Jean, Atkinson, Thomas M.
Publicado no Cancer (2019)

Quantitative method for the determination of Iso-fludelone (KOS-1803) in human plasma by LC-MS/MS

Por Christner, Susan M., Parise, Robert A., Levine, Erica D., Rizvi, Naiyer A., Gounder, Mrinal M., Beumer, Jan H.
Publicado em 2014

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials

Por Hyman, David M., Eaton, Anne A., Gounder, Mrinal M., Pamer, Erika G., Pettiford, Jasmine, Carvajal, Richard D., Ivy, S. Percy, Iasonos, Alexia, Spriggs, David R.
Publicado no Oncotarget (2015)

Nomogram to Predict Cycle-One Serious Drug-Related Toxicity in Phase I Oncology Trials

Por Hyman, David M., Eaton, Anne A., Gounder, Mrinal M., Smith, Gary L., Pamer, Erika G., Hensley, Martee L., Spriggs, David R., Ivy, Percy, Iasonos, Alexia
Publicado em 2014

Toxicity Attribution in Phase I Trials: Evaluating the Effect of Dose on the Frequency of Related and Unrelated Toxicities

Por Eaton, Anne, Iasonos, Alexia, Gounder, Mrinal M, Pamer, Erika G, Drilon, Alexander, Vulih, Diana, Smith, Gary L, Percy Ivy, S., Spriggs, David R, Hyman, David M
Publicado no Clin Cancer Res (2015)

Beyond the Dose-Limiting Toxicity Period: Dermatologic Adverse Events of Patients on Phase 1 Trials of the Cancer Therapeutics Evaluation Program

Por Drilon, Alexander, Eaton, Anne A., Schindler, Katja, Gounder, Mrinal M., Spriggs, David R., Harris, Pamela, Ivy, S. Percy, Iasonos, Alexia, Lacouture, Mario E., Hyman, David M.
Publicado no Cancer (2016)

Activity of sorafenib against desmoid tumor/deep fibromatosis

Por Gounder, Mrinal M, Lefkowitz, Robert A, Keohan, Mary Louise, D’Adamo, David R, Hameed, Meera, Antonescu, Cristina R, Singer, Samuel, Stout, Katherine, Ahn, Linda, Maki, Robert G
Publicado em 2011

A First-in-Human Phase I Study of MORAb-004, a Monoclonal Antibody to Endosialin in Patients with Advanced Solid Tumors

Por Diaz, Luis A., Coughlin, Christina M., C.Weil, Susan, Fishel, Jean, Gounder, Mrinal M., Lawrence, Susan, Azad, Nilofer, O'Shannessy, Daniel J., Grasso, Luigi, Wustner, Jason, Ebel, Wolfgang, Carvajal, Richard D.
Publicado no Clin Cancer Res (2014)

Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors

Por Gounder, Mrinal M., Nayak, Lakshmi, Sahebjam, Solmaz, Muzikansky, Alona, Sanchez, Armando J., Desideri, Serena, Ye, Xiaobu, Ivy, S. Percy, Nabors, L. Burt, Prados, Michael, Grossman, Stuart, DeAngelis, Lisa M., Wen, Patrick Y.
Publicado no J Clin Oncol (2015)

Phase 2 Trial of the CDK4 inhibitor Palbociclib (PD0332991) at 125 mg dose in Well-Differentiated or Dedifferentiated Liposarcoma

Por Dickson, Mark A., Schwartz, Gary K., Keohan, Mary Louise, D’Angelo, Sandra P., Gounder, Mrinal M., Chi, Ping, Antonescu, Cristina R., Landa, Jonathan, Qin, Li-Xuan, Crago, Aimee M., Singer, Samuel, Koff, Andrew, Tap, William D.
Publicado no JAMA Oncol (2016)

Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma

Por Gluck, W. Larry, Gounder, Mrinal M., Frank, Richard, Eskens, Ferry, Blay, Jean Yves, Cassier, Philippe A., Soria, Jean-Charles, Chawla, Sant, de Weger, Vincent, Wagner, Andrew J., Siegel, David, De Vos, Filip, Rasmussen, Erik, Henary, Haby A.
Publicado no Invest New Drugs (2019)

Phase II Trial of the CDK4 Inhibitor PD0332991 in Patients With Advanced CDK4-Amplified Well-Differentiated or Dedifferentiated Liposarcoma

Por Dickson, Mark A., Tap, William D., Keohan, Mary Louise, D'Angelo, Sandra P., Gounder, Mrinal M., Antonescu, Cristina R., Landa, Jonathan, Qin, Li-Xuan, Rathbone, Dustin D., Condy, Mercedes M., Ustoyev, Yelena, Crago, Aimee M., Singer, Samuel, Schwartz, Gary K.
Publicado em 2013

Clinical and Morphologic Characteristics of MEK Inhibitor-Associated Retinopathy: Differences From Central Serous Chorioretinopathy

Por Francis, Jasmine H, Habib, Larissa, Abramson, David H, Yannuzzi, Lawrence A, Heinemann, Murk, Gounder, Mrinal M, Grisham, Rachel N, Postow, Michael A, Shoushtari, Alexander N, Chi, Ping, Segal, Neil H, Yaeger, Rona, Ho, Alan L, Chapman, Paul B, Catalanotti, Federica
Publicado no Ophthalmology (2017)

Phase II Trial of Gemcitabine and Docetaxel with Bevacizumab in Soft Tissue Sarcoma

Por Dickson, Mark A., D'Adamo, David R., Keohan, Mary L., D'Angelo, Sandra P., Carvajal, Richard D., Gounder, Mrinal M., Maki, Robert G., Qin, Li-Xuan, Lefkowitz, Robert A., McKennon, Olivia R., Hirst, Catherine M., Schwartz, Gary K., Tap, William D.
Publicado no Sarcoma (2015)

Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials

Por Yokota, Tomoya, Bendell, Johanna, LoRusso, Patricia, Tsushima, Takahiro, Desai, Ved, Kenmotsu, Hirotsugu, Watanabe, Junichiro, Ono, Akira, Murugesan, Bhavani, Silva, Joseph, Naito, Tateaki, Greenberg, Jonathan, Kumar, Prasanna, Wang, Yibin, Jikoh, Takahiro, Shiga, Ryota, Hyman, David M., Ho, Alan Loh, Spriggs, David R., Schwartz, Gary K., Gounder, Mrinal M.
Publicado no Br J Cancer (2018)

Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived...

Por Stacchiotti, Silvia, Zuco, Valentina, Tortoreto, Monica, Cominetti, Denis, Frezza, Anna Maria, Percio, Stefano, Indio, Valentina, Barisella, Marta, Monti, Valentina, Brich, Silvia, Astolfi, Annalisa, Colombo, Chiara, Pasquali, Sandro, Folini, Marco, Gounder, Mrinal M., Pantaleo, Maria A., Collini, Paola, Dei Tos, Angelo Paolo, Casali, Paolo Giovanni, Gronchi, Alessandro, Zaffaroni, Nadia
Publicado no Cancers (Basel) (2019)