Nomogram to Predict Cycle-One Serious Drug-Related Toxicity in Phase I Oncology Trials

PURPOSE: All patients in phase I trials do not have equivalent susceptibility to serious drug-related toxicity (SDRT). Our goal was to develop a nomogram to predict the risk of cycle-one SDRT to better select appropriate patients for phase I trials. PATIENTS AND METHODS: The prospectively maintained...

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Detalhes bibliográficos
Main Authors: Hyman, David M., Eaton, Anne A., Gounder, Mrinal M., Smith, Gary L., Pamer, Erika G., Hensley, Martee L., Spriggs, David R., Ivy, Percy, Iasonos, Alexia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918535/
https://ncbi.nlm.nih.gov/pubmed/24419130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.49.8808
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