Cell-Free Degradation of p27(kip1), a G(1) Cyclin-Dependent Kinase Inhibitor, Is Dependent on CDK2 Activity and the Proteasome

Por Nguyen, Hoang, Gitig, Diana M., Koff, Andrew
Publicado em 1999

Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase

Por Ciznadija, Daniel, Zhu, Xin-Hua, Koff, Andrew
Publicado em 2011

A U-Rich Element in the 5′ Untranslated Region Is Necessary for the Translation of p27 mRNA

Por Millard, S. Sean, Vidal, Anxo, Markus, Maurice, Koff, Andrew
Publicado em 2000

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

Por Kolluri, Siva Kumar, Weiss, Carsten, Koff, Andrew, Göttlicher, Martin
Publicado em 1999

The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity

Por Raheja, Radhika, Liu, Yuhui, Hukkelhoven, Ellen, Yeh, Nancy, Koff, Andrew
Publicado no Biochem J (2014)

Noncatalytic Requirement for Cyclin A-cdk2 in p27 Turnover

Por Zhu, Xin-Hua, Nguyen, Hoang, Halicka, H. Dorota, Traganos, Frank, Koff, Andrew
Publicado em 2004

Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma

Por Ciznadija, Daniel, Liu, Yuhui, Pyonteck, Stephanie M., Holland, Eric C., Koff, Andrew
Publicado em 2011

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice

Por Park, Michele S., Rosai, Juan, Nguyen, Hai T., Capodieci, Paola, Cordon-Cardo, Carlos, Koff, Andrew
Publicado em 1999

Tyrosine Phosphorylation of the p21 Cyclin-dependent Kinase Inhibitor Facilitates the Development of Proneural Glioma

Por Hukkelhoven, Ellen, Liu, Yuhui, Yeh, Nancy, Ciznadija, Daniel, Blain, Stacy W., Koff, Andrew
Publicado em 2012

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27(Kip1)

Por Casaccia-Bonnefil, Patrizia, Tikoo, Ravi, Kiyokawa, Hiroaki, Friedrich, Victor, Chao, Moses V., Koff, Andrew
Publicado em 1997

p27(kip1) Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation

Por Miller, Jeffrey P., Yeh, Nancy, Hofstetter, Christoph P., Keskin, Doruk, Goldstein, Andrew S., Koff, Andrew
Publicado em 2012

Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27(Kip1) Activity

Por Tsutsui, Tateki, Hesabi, Bahar, Moons, David S., Pandolfi, Pier Paolo, Hansel, Kimberly S., Koff, Andrew, Kiyokawa, Hiroaki
Publicado em 1999

Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27 deficient mice with growth-factor induced oligodendrogliomas

Por See, Wendy L., Miller, Jeffrey P., Squatrito, Massimo, Holland, Eric, Resh, Marilyn D., Koff, Andrew
Publicado em 2010

The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.

Por Mahoney, James A, Odin, Joseph A, White, Sarah M, Shaffer, David, Koff, Andrew, Casciola-Rosen, Livia, Rosen, Antony
Publicado em 2002

Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate

Por Shaffer, David R., Viale, Agnes, Ishiwata, Ryota, Leversha, Margaret, Olgac, Semra, Manova, Katia, Satagopan, Jaya, Scher, Howard, Koff, Andrew
Publicado em 2005

The ETS Protein MEF Is Regulated by Phosphorylation-Dependent Proteolysis via the Protein-Ubiquitin Ligase SCF(Skp2)

Por Liu, Yan, Hedvat, Cyrus V., Mao, Shifeng, Zhu, Xin-Hua, Yao, Jinjuan, Nguyen, Hoang, Koff, Andrew, Nimer, Stephen D.
Publicado em 2006

Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1)

Por Liu, Yuhui, Yeh, Nancy, Zhu, Xin-Hua, Leversha, Margaret, Cordon-Cardo, Carlos, Ghossein, Ronald, Singh, Bhuvanesh, Holland, Eric, Koff, Andrew
Publicado em 2007

CUL4A Abrogation Augments DNA Damage Response and Protection Against Skin Carcinogenesis

Por Liu, Liren, Lee, Sharrell, Zhang, Jianxuan, Peters, Sara B., Hannah, Jeffrey, Zhang, Yue, Yin, Yan, Koff, Andrew, Ma, Liang, Zhou, Pengbo
Publicado em 2009

Bcl-2 Retards Cell Cycle Entry through p27(Kip1), pRB Relative p130, and Altered E2F Regulation

Por Vairo, Gino, Soos, Timothy J., Upton, Todd M., Zalvide, Juan, DeCaprio, James A., Ewen, Mark E., Koff, Andrew, Adams, Jerry M.
Publicado em 2000

p21(cip1) is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal

Por Zezula, Jürgen, Casaccia-Bonnefil, Patrizia, Ezhevsky, Sergei A., Osterhout, Donna J., Levine, Joel M., Dowdy, Steve F., Chao, Moses V., Koff, Andrew
Publicado em 2001