Cell-Free Degradation of p27(kip1), a G(1) Cyclin-Dependent Kinase Inhibitor, Is Dependent on CDK2 Activity and the Proteasome
Entry into S phase is dependent on the coordinated activation of CDK4,6 and CDK2 kinases. Once a cell commits to S phase, there must be a mechanism to ensure the irreversibility of this decision. The activity of these kinases is inhibited by their association with p27. In many cells, p27 plays a maj...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1190 |
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