Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft

Epithelioid sarcoma (ES) is a rare mesenchymal malignancy marked by SMARCB1/INI1 deficiency. Retrospective clinical data report on the activity of anthracycline- and gemcitabine-based regimens. EZH2 inhibitors are currently being tested in clinical trials. Since comparisons of these agents are unlik...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Stacchiotti, Silvia, Zuco, Valentina, Tortoreto, Monica, Cominetti, Denis, Frezza, Anna Maria, Percio, Stefano, Indio, Valentina, Barisella, Marta, Monti, Valentina, Brich, Silvia, Astolfi, Annalisa, Colombo, Chiara, Pasquali, Sandro, Folini, Marco, Gounder, Mrinal M., Pantaleo, Maria A., Collini, Paola, Dei Tos, Angelo Paolo, Casali, Paolo Giovanni, Gronchi, Alessandro, Zaffaroni, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678245/
https://ncbi.nlm.nih.gov/pubmed/31331120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11071015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados