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Molecular basis for primary and secondary tyrosine kinase inhibitor resistance in gastrointestinal stromal tumor
Small molecule kinase inhibitors have irrevocably altered cancer treatment. March 2010 marks the 10th anniversary of using imatinib in gastrointestinal stromal tumors (GIST), a cardinal example of the utility of such targeted therapy in a solid tumor. Before imatinib, metastatic GIST was frustrating...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275340/ https://ncbi.nlm.nih.gov/pubmed/21116624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1526-3 |
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