Results of Tyrosine Kinase Inhibitor Therapy Followed by Surgical Resection for Metastatic Gastrointestinal Stromal Tumor

INTRODUCTION: Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract. Nearly all tumors have an activating mutation in the KIT or, less often, PDGFRα, gene. Therapy with tyrosine kinase inhibitors benefits over 80% of patients with advanced GIST, but most patients e...

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Главные авторы: DeMatteo, Ronald P., Maki, Robert G., Singer, Samuel, Gonen, Mithat, Brennan, Murray F., Antonescu, Cristina R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877004/
https://ncbi.nlm.nih.gov/pubmed/17435539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000236630.93587.59
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