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Brief Report: Phase II Trial of Rebeccamycin Analogue, a Dual Topoisomerase I and II Inhibitor, in Relapsed “Sensitive” Small Cell Lung Cancer

Relapsed small cell lung cancer (SCLC) carries a poor prognosis. Toposiomerase I and II inhibitors and DNA damaging agents are considered amongst the most active agents against SCLC. Rebeccamaycin analogue (RA, Becatacarin) is an anti-tumor antibiotic with inhibitory activity against both topoisomer...

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Dettagli Bibliografici
Autori principali: Schwandt, Anita, Mekhail, Tarek, Halmos, Balazs, O'Brien, Timothy, Ma, Patrick C., Fu, Pingfu, Ivy, Percy, Dowlati, Afshin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310884/
https://ncbi.nlm.nih.gov/pubmed/22425925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31824abca2
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