A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors

Rebeccamycin analog (RA) is an antitumor antibiotic with both topoisomerase I and II inhibiting activity. Topoisomerase inhibitors have demonstrated synergy with platinum agents. We performed a phase I trial of combination RA with oxaliplatin in patients with refractory solid tumors. RA was administ...

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Autores principales: Nock, Charles J., Brell, Joanna M., Bokar, Joseph A., Cooney, Matthew M., Cooper, Brenda, Gibbons, Joseph, Krishnamurthi, Smitha, Manda, Sudhir, Savvides, Panayiotis, Remick, Scot C., Ivy, Percy, Dowlati, Afshin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199744/
https://ncbi.nlm.nih.gov/pubmed/19774342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9322-9
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