Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers

PURPOSE: Advanced cancers of the bile duct and gallbladder carry an ominous prognosis. Rebeccamycin analogue (RA) is a novel antitumor antibiotic where phase I trials suggested clinical efficacy in patients with biliary cancers. METHODS: The primary objective was to determine the response rate to RA...

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Библиографические подробности
Опубликовано в: :Cancer Chemother Pharmacol
Главные авторы: Dowlati, Afshin, Posey, James, Ramanathan, Ramesh K., Rath, Linda, Fu, Pingfu, Chak, Amitabh, Krishnamurthi, Smitha, Brell, Joanna, Ingalls, Stephen, Hoppel, Charles L., Ivy, Percy, Remick, Scot C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220168/
https://ncbi.nlm.nih.gov/pubmed/19399502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1005-x
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