ME-07 INFLUENCE OF REGIONAL MICROENVIROMENT AND ASTROCYTE HETEROGENEITY ON ASTROCYTOMA DEVELOPMENT

Por Irvin, David, Schmid, Ralf, Bash, Ryan, Miller, C. Ryan
Publicado em 2014

BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea–Induced Gliomagenesis

Por McNeill, Robert S., Irvin, David M., Miller, C. Ryan
Publicado no Am J Pathol (2016)

Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models

Por Irvin, David M., McNeill, Robert S., Bash, Ryan E., Miller, C. Ryan
Publicado no Brain Pathol (2016)

CBIO-18. G-QUADRUPLEX STABILIZATION TARGETS ATRX-DEFICIENT HIGH-GRADE GLIOMA VIA INDUCTION OF p53-INDEPENDENT APOPTOSIS

Por Dharmaiah, Sharvari, Farooqi, Ahsan, Alvarez, Christian, Sharin, Vladislav, Irvin, David, Huse, Jason
Publicado no Neuro Oncol (2020)

CSIG-09. ATRX DEFICIENCY IN GLIOMA IMPACTS TRANSCRIPTIONAL PROFILES AND THE IMMUNE MICROENVIRONMENT IN VIVO

Por Irvin, David, Roberts, Hannah, Sharin, Vladislav, Farooqi, Ahsan, Dharmaiah, Sharvari, Alvarez, Christian, Huse, Jason
Publicado no Neuro Oncol (2020)

Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model

Por Okolie, Onyinyechukwu, Bago, Juli R., Schmid, Ralf S., Irvin, David M., Bash, Ryan E., Miller, C. Ryan, Hingtgen, Shawn D.
Publicado no Neuro Oncol (2016)

Identification of patient-derived glioblastoma stem cell (GSC) lines with the alternative lengthening of telomeres phenotype

Por Farooqi, Ahsan, Yang, Jie, Sharin, Vladislav, Ezhilarasan, Ravesanker, Danussi, Carla, Alvarez, Christian, Dharmaiah, Sharvari, Irvin, David, Huse, Jason, Sulman, Erik P.
Publicado no Acta Neuropathol Commun (2019)

PDTM-18. INVESTIGATING INTRA-CAVITY NEURAL STEM CELL THERAPY FOR POST-SURGICAL DISEASE IN A NOVEL SURGICAL RESECTION/RECURRENCE MODEL OF MEDULLOBLASTOMA

Por Okolie, Onyinyechukwu, Finch, Elizabeth, Irvin, David, Bago, Juli, Sheets, Kevin, Satterlee, Andrew, Dumitru, Raluca, Khagi, Simon, Elton, Scott, Ewend, Matthew, Hingtgen, Shawn
Publicado no Neuro Oncol (2017)

IMMU-18. INTERPLAY BETWEEN IDH1 AND ATRX MUTATIONS GOVERN INNATE IMMUNE RESPONSES IN GLIOMAS

Por Hariharan, Seethalakshmi, Bowie, Michelle, Hostettler, Janell, Roso, Kristen, He, Yiping, Roskoski, Martin A, Charbonneau, Casey, Keir, Stephen, Brown, Michael, Irvin, David, Zhang, Gao, Gromeier, Matthias, Huse, Jason, Ashley, David
Publicado no Neuro Oncol (2020)

Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection

Por Okolie, Onyinyechukwu, Irvin, David M., Bago, Juli R., Sheets, Kevin, Satterlee, Andrew, Carey-Ewend, Abigail G., Lettry, Vivien, Dumitru, Raluca, Elton, Scott, Ewend, Matthew G., Miller, C. Ryan, Hingtgen, Shawn D.
Publicado no PLoS One (2018)

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma

Por Vitucci, Mark, Irvin, David M, McNeill, Robert S, Schmid, Ralf S, Simon, Jeremy M, Dhruv, Harshil D, Siegel, Marni B, Werneke, Andrea M, Bash, Ryan E, Kim, Seungchan, Berens, Michael E, Miller, C Ryan
Publicado no Neuro Oncol (2017)

Vascular channels formed by subpopulations of PECAM1(+) melanoma cells

Por Dunleavey, James M., Xiao, Lin, Thompson, Joshua, Kim, Mi Mi, Shields, Janiel M., Shelton, Sarah E., Irvin, David M., Brings, Victoria E., Ollila, David, Brekken, Rolf A., Dayton, Paul A., Melero-Martin, Juan M., Dudley, Andrew C.
Publicado no Nat Commun (2014)

MerTK as a therapeutic target in glioblastoma

Por Wu, Jing, Frady, Lauren N, Bash, Ryan E, Cohen, Stephanie M, Schorzman, Allison N, Su, Yu-Ting, Irvin, David M, Zamboni, William C, Wang, Xiaodong, Frye, Stephen V, Ewend, Matthew G, Sulman, Erik P, Gilbert, Mark R, Earp, H Shelton, Miller, C Ryan
Publicado no Neuro Oncol (2018)

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma

Por McNeill, Robert S, Canoutas, Demitra A, Stuhlmiller, Timothy J, Dhruv, Harshil D, Irvin, David M, Bash, Ryan E, Angus, Steven P, Herring, Laura E, Simon, Jeremy M, Skinner, Kasey R, Limas, Juanita C, Chen, Xin, Schmid, Ralf S, Siegel, Marni B, Van Swearingen, Amanda E D, Hadler, Michael J, Sulman, Erik P, Sarkaria, Jann N, Anders, Carey K, Graves, Lee M, Berens, Michael E, Johnson, Gary L, Miller, C Ryan
Publicado no Neuro Oncol (2017)