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ME-07 INFLUENCE OF REGIONAL MICROENVIROMENT AND ASTROCYTE HETEROGENEITY ON ASTROCYTOMA DEVELOPMENT
The role of the local microenvironment during early astrocytoma development remains elusive. We previously showed that Rb and Pten inactivation and Kras activation (TRP) transforms Gfap(+) astrocytes and induces low-grade astrocytoma tumorigenesis throughout the adult brain. To confirm that astrocyt...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218308/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou261.6 |
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