Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

Current astrocytoma models are limited in their ability to define the roles of oncogenic mutations in specific brain cell types during disease pathogenesis and their utility for preclinical drug development. In order to design a better model system for these applications, phenotypically wild-type co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Vis Exp
Prif Awduron: McNeill, Robert S., Schmid, Ralf S., Bash, Ryan E., Vitucci, Mark, White, Kristen K., Werneke, Andrea M., Constance, Brian H., Huff, Byron, Miller, C. Ryan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2014
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827968/
https://ncbi.nlm.nih.gov/pubmed/25146643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51763
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg