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Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

Current astrocytoma models are limited in their ability to define the roles of oncogenic mutations in specific brain cell types during disease pathogenesis and their utility for preclinical drug development. In order to design a better model system for these applications, phenotypically wild-type co...

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Bibliografische gegevens
Gepubliceerd in:J Vis Exp
Hoofdauteurs: McNeill, Robert S., Schmid, Ralf S., Bash, Ryan E., Vitucci, Mark, White, Kristen K., Werneke, Andrea M., Constance, Brian H., Huff, Byron, Miller, C. Ryan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827968/
https://ncbi.nlm.nih.gov/pubmed/25146643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51763
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