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Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models

The influence of cellular origin on glioma pathogenesis remains elusive. We previously showed that mutations inactivating Rb and Pten and activating Kras transform astrocytes and induce tumorigenesis throughout the adult mouse brain. However, it remained unclear whether astrocyte subpopulations were...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain Pathol
Egile Nagusiak: Irvin, David M., McNeill, Robert S., Bash, Ryan E., Miller, C. Ryan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322824/
https://ncbi.nlm.nih.gov/pubmed/26762242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12348
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