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Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models

The influence of cellular origin on glioma pathogenesis remains elusive. We previously showed that mutations inactivating Rb and Pten and activating Kras transform astrocytes and induce tumorigenesis throughout the adult mouse brain. However, it remained unclear whether astrocyte subpopulations were...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Irvin, David M., McNeill, Robert S., Bash, Ryan E., Miller, C. Ryan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322824/
https://ncbi.nlm.nih.gov/pubmed/26762242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12348
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