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ME-07 INFLUENCE OF REGIONAL MICROENVIROMENT AND ASTROCYTE HETEROGENEITY ON ASTROCYTOMA DEVELOPMENT

The role of the local microenvironment during early astrocytoma development remains elusive. We previously showed that Rb and Pten inactivation and Kras activation (TRP) transforms Gfap(+) astrocytes and induces low-grade astrocytoma tumorigenesis throughout the adult brain. To confirm that astrocyt...

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Detalles Bibliográficos
Main Authors: Irvin, David, Schmid, Ralf, Bash, Ryan, Miller, C. Ryan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218308/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou261.6
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