MerTK as a therapeutic target in glioblastoma

BACKGROUND: Glioma-associated macrophages and microglia (GAMs) are components of the glioblastoma (GBM) microenvironment that express MerTK, a receptor tyrosine kinase that triggers efferocytosis and can suppress innate immune responses. The aim of the study was to define MerTK as a therapeutic targ...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wu, Jing, Frady, Lauren N, Bash, Ryan E, Cohen, Stephanie M, Schorzman, Allison N, Su, Yu-Ting, Irvin, David M, Zamboni, William C, Wang, Xiaodong, Frye, Stephen V, Ewend, Matthew G, Sulman, Erik P, Gilbert, Mark R, Earp, H Shelton, Miller, C Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761530/
https://ncbi.nlm.nih.gov/pubmed/28605477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox111
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