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MerTK regulates thymic selection of autoreactive T cells

T cell-mediated autoimmune diseases such as type 1 diabetes (T1D) are believed to be the result in part of inefficient negative selection of self-specific thymocytes. However, the events regulating thymic negative selection are not fully understood. In the current study, we demonstrate that nonobese...

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Detalhes bibliográficos
Main Authors: Wallet, Mark A., Flores, Rafael R., Wang, Yaming, Yi, Zuoan, Kroger, Charles J., Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Wang, Bo, Tisch, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660755/
https://ncbi.nlm.nih.gov/pubmed/19251650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900683106
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