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A novel role for c-Src and STAT3 in apoptotic cell–mediated MerTK-dependent immunoregulation of dendritic cells

Dendritic cells (DCs) play an instrumental role in regulating tolerance to self-antigens and preventing autoimmunity. One mechanism by which “tolerogenic” DCs are established is through the inhibitory effects of apoptotic cells (ACs). Immature DCs encountering ACs are resistant to stimuli that activ...

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Detalhes bibliográficos
Main Authors: Yi, Zuoan, Li, Li, Matsushima, Glenn K., Earp, H. Shelton, Wang, Bo, Tisch, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759647/
https://ncbi.nlm.nih.gov/pubmed/19667404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-207522
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