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Apoptotic cells induce Mer tyrosine kinase–dependent blockade of NF-κB activation in dendritic cells

Dendritic cells (DCs) play a key role in immune homeostasis and maintenance of self-tolerance. Tolerogenic DCs can be established by an encounter with apoptotic cells (ACs) and subsequent inhibition of maturation and effector functions. The receptor(s) and signaling pathway(s) involved in AC-induced...

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Detalhes bibliográficos
Main Authors: Sen, Pradip, Wallet, Mark A., Yi, Zuoan, Huang, Yingsu, Henderson, Michael, Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Baldwin, Albert S., Tisch, Roland M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785106/
https://ncbi.nlm.nih.gov/pubmed/17008547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-017368
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