A carregar...

EXTH-44. INHIBITION OF MerTK ACTIVATES GLIOBLASTOMA-ASSOCIATED MACROPHAGES AND INDUCES TUMOR CELL DEATH IN GLIOMA MICROENVIRONMENT

BACKGROUND: Glioblastoma-associated macrophages and microglia (GAMs) are the predominant immune cells in the tumor microenvironment. Activation of MerTK, a receptor tyrosine kinase, triggers efferocytosis and polarizes GAMs to an immunosuppressive phenotype, promoting glioma growth. Our previous fin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Su, Yu-Ting, Butler, Madison, Hwang, Lee, Maric, Dragan, Earp, Shelton, Terabe, Masaki, Gilbert, Mark, Wu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847213/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.376
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!