CSIG-09. ATRX DEFICIENCY IN GLIOMA IMPACTS TRANSCRIPTIONAL PROFILES AND THE IMMUNE MICROENVIRONMENT IN VIVO

Current treatment for diffuse astrocytoma fails to address its underlying molecular mechanisms leading to inevitable disease progression and eventual patient death. Genomic studies have implicated ATRX alterations as critical to low grade glioma biology. Our lab has previously shown in vitro that AT...

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Publicat a:Neuro Oncol
Autors principals: Irvin, David, Roberts, Hannah, Sharin, Vladislav, Farooqi, Ahsan, Dharmaiah, Sharvari, Alvarez, Christian, Huse, Jason
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Cell Signaling and Signaling Pathways
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650482/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.121
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