CSIG-09. ATRX DEFICIENCY IN GLIOMA IMPACTS TRANSCRIPTIONAL PROFILES AND THE IMMUNE MICROENVIRONMENT IN VIVO

Current treatment for diffuse astrocytoma fails to address its underlying molecular mechanisms leading to inevitable disease progression and eventual patient death. Genomic studies have implicated ATRX alterations as critical to low grade glioma biology. Our lab has previously shown in vitro that AT...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Irvin, David, Roberts, Hannah, Sharin, Vladislav, Farooqi, Ahsan, Dharmaiah, Sharvari, Alvarez, Christian, Huse, Jason
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Cell Signaling and Signaling Pathways
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650482/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.121
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