Heterogeneity, Self-Renewal, and Differentiation of Hematopoietic Stem Cells

Por Jurecic, Roland, Li, Linheng, Humphries, R. Keith
Publicado em 2012

Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis

Por Rawat, Vijay P. S., Humphries, R. Keith, Buske, Christian
Publicado em 2012

Differential and Common Leukemogenic Potentials of Multiple NUP98-Hox Fusion Proteins Alone or with Meis1

Por Pineault, Nicolas, Abramovich, Carolina, Ohta, Hideaki, Humphries, R. Keith
Publicado em 2004

Candidate Genes for Expansion and Transformation of Hematopoietic Stem Cells by NUP98-HOX Fusion Genes

Por Palmqvist, Lars, Pineault, Nicolas, Wasslavik, Carina, Humphries, R. Keith
Publicado em 2007

A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22)

Por Moon, Yeonsook, Horsman, Douglas E., Humphries, R. Keith, Park, Gyeongsin
Publicado em 2013

Insights into leukemia initiating cell frequency and self-renewal from a novel canine model of leukemia

Por Imren, Suzan, Zhang, Xiao-Bing, Humphries, R. Keith, Kiem, Hans-Peter
Publicado em 2010

Sustained In Vitro Trigger of Self-Renewal Divisions in Hoxb4(hi)Pbx1(lo) Hematopoietic Stem Cells

Por Cellot, Sonia, Krosl, Jana, Chagraoui, Jalila, Meloche, Sylvain, Humphries, R. Keith, Sauvageau, Guy
Publicado em 2007

Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion

Por Miller, Michelle Erin, Rosten, Patty, Lemieux, Madeleine E., Lai, Courteney, Humphries, R. Keith
Publicado no PLoS One (2016)

Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells

Por Watts, Korashon L., Delaney, Colleen, Humphries, R. Keith, Bernstein, Irwin D., Kiem, Hans-Peter
Publicado em 2010

The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

Por Huber, Michael, Helgason, Cheryl D., Damen, Jacqueline E., Liu, Ling, Humphries, R. Keith, Krystal, Gerald
Publicado em 1998

Differential Effects of HOXB4 on Nonhuman Primate Short- and Long-Term Repopulating Cells

Por Zhang, Xiao-Bing, Beard, Brian C, Beebe, Katherine, Storer, Barry, Humphries, R. Keith, Kiem, Hans-Peter
Publicado em 2006

Functional Regulation of Pre-B-cell Leukemia Homeobox Interacting Protein 1 (PBXIP1/HPIP) in Erythroid Differentiation

Por Manavathi, Bramanandam, Lo, Dennis, Bugide, Suresh, Dey, Oindrilla, Imren, Suzan, Weiss, Mitchell J., Humphries, R. Keith
Publicado em 2012

Lentiviral Fluorescent Genetic Barcoding for Multiplex Fate Tracking of Leukemic Cells

Por Maetzig, Tobias, Ruschmann, Jens, Sanchez Milde, Lea, Lai, Courteney K., von Krosigk, Niklas, Humphries, R. Keith
Publicado no Mol Ther Methods Clin Dev (2017)

Myelosuppressive Conditioning Using Busulfan Enables Bone Marrow Cell Accumulation in the Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

Por Lewis, Coral-Ann B., Manning, John, Barr, Christine, Peake, Kyle, Humphries, R. Keith, Rossi, Fabio, Krieger, Charles
Publicado em 2013

Polycomb Group Gene rae28 Is Required for Sustaining Activity of Hematopoietic Stem Cells

Por Ohta, Hideaki, Sawada, Akihisa, Kim, Ji Yoo, Tokimasa, Sadao, Nishiguchi, Seiji, Humphries, R. Keith, Hara, Junichi, Takihara, Yoshihiro
Publicado em 2002

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

Por Lawrence, H. Jeffrey, Christensen, Julie, Fong, Stephen, Hu, Yu-Long, Weissman, Irving, Sauvageau, Guy, Humphries, R. Keith, Largman, Corey
Publicado em 2005

A Dual Role for Src Homology 2 Domain–Containing Inositol-5-Phosphatase (Ship) in Immunity: Aberrant Development and Enhanced Function of B Lymphocytes in Ship(−/)− Mice

Por Helgason, Cheryl D., Kalberer, Christian P., Damen, Jacqueline E., Chappel, Suzanne M., Pineault, Nicolas, Krystal, Gerald, Humphries, R. Keith
Publicado em 2000

CD34(+) Expansion With Delta-1 and HOXB4 Promotes Rapid Engraftment and Transfusion Independence in a Macaca nemestrina Cord Blood Transplant Model

Por Watts, Korashon L, Delaney, Colleen, Nelson, Veronica, Trobridge, Grant D, Beard, Brian C, Humphries, R Keith, Kiem, Hans-Peter
Publicado em 2013

Altered responsiveness to chemokines due to targeted disruption of SHIP

Por Kim, Chang H., Hangoc, Giao, Cooper, Scott, Helgason, Cheryl D., Yew, Sandie, Humphries, R. Keith, Krystal, Gerald, Broxmeyer, Hal E.
Publicado em 1999

Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions

Por Ohta, Hideaki, Sekulovic, Sanja, Bakovic, Silvia, Eaves, Connie J., Pineault, Nicolas, Gasparetto, Maura, Smith, Clayton, Sauvageau, Guy, Humphries, R. Keith
Publicado em 2007