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CD34(+) Expansion With Delta-1 and HOXB4 Promotes Rapid Engraftment and Transfusion Independence in a Macaca nemestrina Cord Blood Transplant Model

Umbilical cord blood (CB) transplantation is a promising therapeutic approach but continues to be associated with delayed engraftment and infections. Here, we explored in our macaque CB transplant model expansion and engraftment kinetics of cells expanded with the combination of HOXB4 and Delta-1. C...

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Detalhes bibliográficos
Main Authors: Watts, Korashon L, Delaney, Colleen, Nelson, Veronica, Trobridge, Grant D, Beard, Brian C, Humphries, R Keith, Kiem, Hans-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677311/
https://ncbi.nlm.nih.gov/pubmed/23587923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.40
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