A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22)

Translocations involving chromosome 21q22 are frequently observed in hematologic malignancies including acute myeloid leukemia (AML), most of which have been known to be involved in malignant transformation through transcriptional dysregulation of Runt-related transcription factor 1 (RUNX1) target g...

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Autori principali: Moon, Yeonsook, Horsman, Douglas E., Humphries, R. Keith, Park, Gyeongsin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Association of Immunologists 2013
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817305/
https://ncbi.nlm.nih.gov/pubmed/24198749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2013.13.5.222
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