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Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions

OBJECTIVE: Strategies to expand hematopoietic stem cells (HSCs) ex vivo are of key interest. The objective of this study was to resolve if ability of HOXB4, previously documented to induce a significant expansion of HSCs in culture, may extend to other HOX genes and also to further analyze the HOX s...

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Detalhes bibliográficos
Main Authors: Ohta, Hideaki, Sekulovic, Sanja, Bakovic, Silvia, Eaves, Connie J., Pineault, Nicolas, Gasparetto, Maura, Smith, Clayton, Sauvageau, Guy, Humphries, R. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774852/
https://ncbi.nlm.nih.gov/pubmed/17577930
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