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Sustained In Vitro Trigger of Self-Renewal Divisions in Hoxb4(hi)Pbx1(lo) Hematopoietic Stem Cells
Factors that trigger and sustain self-renewal divisions in tissue stem cells remain poorly characterized. By modulating the levels of Hoxb4 and its co-factor Pbx1 in primary hematopoietic cells (Hoxb4(hi)Pbx1(lo)cells), we report an in vitro expansion of mouse hematopoietic stem cells (HSCs) by 10(5...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752385/ https://ncbi.nlm.nih.gov/pubmed/17577929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2007.02.013 |
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