E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells

The Polycomb group gene Bmi1 is essential for the proliferation of neural and hematopoietic stem cells. Much remains to be learned about the pathways involved in the severe hematopoietic phenotype observed in Bmi1 homozygous mutant mice except for the fact that loss of p53 or concomitant loss of p16...

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Autors principals: Chagraoui, Jalila, Niessen, Sherry L., Lessard, Julie, Girard, Simon, Coulombe, Philippe, Sauvageau, Martin, Meloche, Sylvain, Sauvageau, Guy
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536061/
https://ncbi.nlm.nih.gov/pubmed/16882984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1453406
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