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An anticlastogenic function for the Polycomb Group gene Bmi1

BMI1 is a key component of multiprotein Polycomb repression complex 1 (PRC1), and its disruption in mice induces severe aplastic anemia by early adulthood. The contributing mechanisms responsible for this phenotype remain elusive. Here we show that transformed human cell lines as well as primitive h...

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Bibliografische gegevens
Hoofdauteurs: Chagraoui, Jalila, Hébert, Josée, Girard, Simon, Sauvageau, Guy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069154/
https://ncbi.nlm.nih.gov/pubmed/21402923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014263108
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