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An anticlastogenic function for the Polycomb Group gene Bmi1
BMI1 is a key component of multiprotein Polycomb repression complex 1 (PRC1), and its disruption in mice induces severe aplastic anemia by early adulthood. The contributing mechanisms responsible for this phenotype remain elusive. Here we show that transformed human cell lines as well as primitive h...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069154/ https://ncbi.nlm.nih.gov/pubmed/21402923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014263108 |
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