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Polycomb Group Genes: Keeping Stem Cell Activity in Balance

Overexpression of Polycomb group genes is often associated with cancer development, whereas complete deletion results in loss of stem cell activity. New studies show that partial loss of function of Polycomb group genes enhances the activity of blood stem/progenitor cells.

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Hlavní autoři: Sauvageau, Martin, Sauvageau, Guy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689701/
https://ncbi.nlm.nih.gov/pubmed/18447587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060113
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