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Polycomb Group Genes: Keeping Stem Cell Activity in Balance

Overexpression of Polycomb group genes is often associated with cancer development, whereas complete deletion results in loss of stem cell activity. New studies show that partial loss of function of Polycomb group genes enhances the activity of blood stem/progenitor cells.

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Detalhes bibliográficos
Main Authors: Sauvageau, Martin, Sauvageau, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689701/
https://ncbi.nlm.nih.gov/pubmed/18447587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060113
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