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Myelosuppressive Conditioning Using Busulfan Enables Bone Marrow Cell Accumulation in the Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

Myeloablative preconditioning using irradiation is the most commonly used technique to generate rodents having chimeric bone marrow, employed for the study of bone marrow-derived cell accumulation in the healthy and diseased central nervous system. However, irradiation has been shown to alter the bl...

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Detalhes bibliográficos
Main Authors: Lewis, Coral-Ann B., Manning, John, Barr, Christine, Peake, Kyle, Humphries, R. Keith, Rossi, Fabio, Krieger, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620474/
https://ncbi.nlm.nih.gov/pubmed/23593276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060661
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