Two successful decades of Swiss collaborations to develop new anti-malarials

door Hooft van Huijsduijnen, Rob, Wells, Timothy, Tanner, Marcel, Wittlin, Sergio
Gepubliceerd in Malar J (2019)

Profile of William C. Campbell, Satoshi Ōmura, and Youyou Tu, 2015 Nobel Laureates in Physiology or Medicine

door Van Voorhis, Wesley C., Hooft van Huijsduijnen, Rob, Wells, Timothy N. C.
Gepubliceerd in Proc Natl Acad Sci U S A (2015)

Designing the next generation of medicines for malaria control and eradication

door Burrows, Jeremy N, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J, Oeuvray, Claude, Wells, Timothy NC
Gepubliceerd in 2013

Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers

door McCarthy, James S., Baker, Mark, O'Rourke, Peter, Marquart, Louise, Griffin, Paul, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Gepubliceerd in J Antimicrob Chemother (2016)

Reassessing therapeutic antibodies for neglected and tropical diseases

door Hooft van Huijsduijnen, Rob, Kojima, Somei, Carter, Dee, Okabe, Hisafumi, Sato, Akihide, Akahata, Wataru, Wells, Timothy N. C., Katsuno, Kei
Gepubliceerd in PLoS Negl Trop Dis (2020)

Protein tyrosine phosphatases in glioma biology

door Navis, Anna C., van den Eijnden, Monique, Schepens, Jan T. G., Hooft van Huijsduijnen, Rob, Wesseling, Pieter, Hendriks, Wiljan J. A. J.
Gepubliceerd in 2009

A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria

door Burrows, Jeremy, Slater, Hannah, Macintyre, Fiona, Rees, Sarah, Thomas, Anna, Okumu, Fredros, Hooft van Huijsduijnen, Rob, Duparc, Stephan, Wells, Timothy N. C.
Gepubliceerd in Malar J (2018)

New developments in anti-malarial target candidate and product profiles

door Burrows, Jeremy N., Duparc, Stephan, Gutteridge, Winston E., Hooft van Huijsduijnen, Rob, Kaszubska, Wiweka, Macintyre, Fiona, Mazzuri, Sébastien, Möhrle, Jörg J., Wells, Timothy N. C.
Gepubliceerd in Malar J (2017)

Both Intrinsic Substrate Preference and Network Context Contribute to Substrate Selection of Classical Tyrosine Phosphatases

door Palma, Anita, Tinti, Michele, Paoluzi, Serena, Santonico, Elena, Brandt, Bernd Willem, Hooft van Huijsduijnen, Rob, Masch, Antonia, Heringa, Jaap, Schutkowski, Mike, Castagnoli, Luisa, Cesareni, Gianni
Gepubliceerd in J Biol Chem (2017)

Anticancer Properties of Distinct Antimalarial Drug Classes

door Hooft van Huijsduijnen, Rob, Guy, R. Kiplin, Chibale, Kelly, Haynes, Richard K., Peitz, Ingmar, Kelter, Gerhard, Phillips, Margaret A., Vennerstrom, Jonathan L., Yuthavong, Yongyuth, Wells, Timothy N. C.
Gepubliceerd in 2013

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

door McCarthy, James S., Rückle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O’Rourke, Peter, Griffin, Paul, Marquart, Louise, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Gepubliceerd in Malar J (2016)

Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies

door Nagaraju, Kanneboyina, Raben, Nina, Loeffler, Lisa, Parker, Tomasina, Rochon, Paul J., Lee, Eunice, Danning, Carol, Wada, Ryuichi, Thompson, Cynthia, Bahtiyar, Gul, Craft, Joseph, Hooft van Huijsduijnen, Rob, Plotz, Paul
Gepubliceerd in 2000

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria

door Macintyre, Fiona, Ramachandruni, Hanu, Burrows, Jeremy N., Holm, René, Thomas, Anna, Möhrle, Jörg J., Duparc, Stephan, Hooft van Huijsduijnen, Rob, Greenwood, Brian, Gutteridge, Winston E., Wells, Timothy N. C., Kaszubska, Wiweka
Gepubliceerd in Malar J (2018)

Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma

door Bourgonje, Annika M., Verrijp, Kiek, Schepens, Jan T. G., Navis, Anna C., Piepers, Jolanda A. F., Palmen, Chantal B. C., van den Eijnden, Monique, Hooft van Huijsduijnen, Rob, Wesseling, Pieter, Leenders, William P. J., Hendriks, Wiljan J. A. J.
Gepubliceerd in Acta Neuropathol Commun (2016)

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines

door Alirol, Emilie, Wi, Teodora E., Bala, Manju, Bazzo, Maria Luiza, Chen, Xiang-Sheng, Deal, Carolyn, Dillon, Jo-Anne R., Kularatne, Ranmini, Heim, Jutta, Hooft van Huijsduijnen, Rob, Hook, Edward W., Lahra, Monica M., Lewis, David A., Ndowa, Francis, Shafer, William M., Tayler, Liz, Workowski, Kimberly, Unemo, Magnus, Balasegaram, Manica
Gepubliceerd in PLoS Med (2017)

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax mal...

door Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan
Gepubliceerd in Lancet Infect Dis (2018)

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

door Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Gepubliceerd in PLoS Pathog (2016)