A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

BACKGROUND: Ferroquine (SSR97193) is a candidate anti-malarial currently undergoing clinical trials for malaria. To better understand its pharmacokinetic (PK) and pharmacodynamic (PD) parameters the compound was tested in the experimentally induced blood stage malaria infection model in volunteers....

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Vydáno v:Malar J
Hlavní autoři: McCarthy, James S., Rückle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O’Rourke, Peter, Griffin, Paul, Marquart, Louise, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022189/
https://ncbi.nlm.nih.gov/pubmed/27624471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1511-3
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