Piperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia

Background. Piperaquine, coformulated with dihydroartemisinin, is a component of a widely used artemisinin combination therapy. There is a paucity of data on its antimalarial activity as a single agent. Such data, if available, would inform selection of new coformulations. Methods. We undertook a st...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Pasay, Cielo J., Rockett, Rebecca, Sekuloski, Silvana, Griffin, Paul, Marquart, Louise, Peatey, Christopher, Wang, Claire Y. T., O'Rourke, Peter, Elliott, Suzanne, Baker, Mark, Möhrle, Jörg J., McCarthy, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907420/
https://ncbi.nlm.nih.gov/pubmed/27056954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw128
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