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A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs

BACKGROUND: Critical to the development of new drugs for treatment of malaria is the capacity to safely evaluate their activity in human subjects. The approach that has been most commonly used is testing in subjects with natural malaria infection, a methodology that may expose symptomatic subjects t...

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主要な著者: McCarthy, James S., Sekuloski, Silvana, Griffin, Paul M., Elliott, Suzanne, Douglas, Nanette, Peatey, Chris, Rockett, Rebecca, O'Rourke, Peter, Marquart, Louise, Hermsen, Cornelius, Duparc, Stephan, Möhrle, Jörg, Trenholme, Katharine R., Humberstone, Andrew J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159571/
https://ncbi.nlm.nih.gov/pubmed/21887214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021914
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