A Specific Domain of the Chikungunya Virus E2 Protein Regulates Particle Formation in Human Cells: Implications for Alphavirus Vaccine Design

Por Akahata, Wataru, Nabel, Gary J.
Publicado em 2012

Comparative Immunogenicity of Human Immunodeficiency Virus Particles and Corresponding Polypeptides in a DNA Vaccine

Por Akahata, Wataru, Yang, Zhi-yong, Nabel, Gary J.
Publicado em 2005

Structural studies of Chikungunya virus maturation

Por Yap, Moh Lan, Klose, Thomas, Urakami, Akane, Hasan, S. Saif, Akahata, Wataru, Rossmann, Michael G.
Publicado no Proc Natl Acad Sci U S A (2017)

Protein Methyltransferase 2 Inhibits NF-κB Function and Promotes Apoptosis

Por Ganesh, Lakshmanan, Yoshimoto, Takanobu, Moorthy, Narayani C., Akahata, Wataru, Boehm, Manfred, Nabel, Elizabeth G., Nabel, Gary J.
Publicado em 2006

Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission

Por Porta, Jason, Mangala Prasad, Vidya, Wang, Cheng-I, Akahata, Wataru, Ng, Lisa F. P., Rossmann, Michael G.
Publicado no J Virol (2016)

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

Por Sun, Siyang, Xiang, Ye, Akahata, Wataru, Holdaway, Heather, Pal, Pankaj, Zhang, Xinzheng, Diamond, Michael S, Nabel, Gary J, Rossmann, Michael G
Publicado em 2013

An Envelope-Modified Tetravalent Dengue Virus-Like-Particle Vaccine Has Implications for Flavivirus Vaccine Design

Por Urakami, Akane, Ngwe Tun, Mya Myat, Moi, Meng Ling, Sakurai, Atsuko, Ishikawa, Momoko, Kuno, Sachiko, Ueno, Ryuji, Morita, Kouichi, Akahata, Wataru
Publicado no J Virol (2017)

A VLP vaccine for epidemic Chikungunya virus protects non-human primates against infection

Por Akahata, Wataru, Yang, Zhi-yong, Andersen, Hanne, Sun, Siyang, Holdaway, Heather A., Kong, Wing-Pui, Lewis, Mark G., Higgs, Stephen, Rossmann, Michael G., Rao, Srinivas, Nabel, Gary J.
Publicado em 2010

Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus

Por Urakami, Akane, Sakurai, Atsuko, Ishikawa, Momoko, Yap, Moh Lan, Flores-Garcia, Yevel, Haseda, Yasunari, Aoshi, Taiki, Zavala, Fidel P., Rossmann, Michael G., Kuno, Sachiko, Ueno, Ryuji, Akahata, Wataru
Publicado no Clin Vaccine Immunol (2017)

Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity

Por Long, Feng, Fong, Rachel H., Austin, Stephen K., Chen, Zhenguo, Klose, Thomas, Fokine, Andrei, Liu, Yue, Porta, Jason, Sapparapu, Gopal, Akahata, Wataru, Doranz, Benjamin J., Crowe, James E., Diamond, Michael S., Rossmann, Michael G.
Publicado no Proc Natl Acad Sci U S A (2015)

Different Vaccine Vectors Delivering the Same Antigen Elicit CD8(+) T Cell Responses with Distinct Clonotype and Epitope Specificity

Por Honda, Mitsuo, Wang, Rui, Kong, Wing-Pui, Kanekiyo, Masaru, Akahata, Wataru, Xu, Ling, Matsuo, Kazuhiro, Natarajan, Kannan, Robinson, Howard, Asher, Tedi E., Price, David A., Douek, Daniel C., Margulies, David H., Nabel, Gary J.
Publicado em 2009

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

Por Pal, Pankaj, Dowd, Kimberly A., Brien, James D., Edeling, Melissa A., Gorlatov, Sergey, Johnson, Syd, Lee, Iris, Akahata, Wataru, Nabel, Gary J., Richter, Mareike K. S., Smit, Jolanda M., Fremont, Daved H., Pierson, Theodore C., Heise, Mark T., Diamond, Michael S.
Publicado em 2013